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by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated Article

Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang

Engineering 2023, Volume 20, Issue 1,   Pages 63-76 doi: 10.1016/j.eng.2021.09.007

Abstract: Transcriptomic profiling suggested that genes related to macrophage function were differently expressedConsequently, the effects of XFBD on macrophage activation and mobilization were investigated in a macrophageXFBD exerts strong inhibitory effects on both macrophage activation and migration.em>, and Citri grandis Exocarpium rubrum, were then found to strongly downregulate macrophagemigration, while the presence of ephedrine, atractylenolide, and kaempferol was attributed to these

Keywords： Xuanfeibaidu Formula     Multimodal identification     Inflammation     Macrophage activation     Macrophage migration    

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Theoretical study on the mechanism of sulfur migration to gas in the pyrolysis of benzothiophene

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 3,   Pages 334-346 doi: 10.1007/s11705-022-2209-4

Abstract: derivatives are important intermediates for the sulfur gas release from organic sulfur, but the underlying migrationHerein, the mechanism of sulfur migration during the release of sulfur-containing radicals in benzothiopheneThis study lays a foundation for elucidating sulfur migration mechanisms and furthering the development

Keywords： benzothiophene     sulfur migration     pyrolysis     density functional theory    

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Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 781-795 doi: 10.1007/s11684-023-0986-x

Abstract: Tear film hyperosmolarity plays a core role in the development of dry eye disease (DED) by mediating the disruption of ocular surface homeostasis and triggering inflammation in ocular surface epithelium. In this study, the mechanisms involving the hyperosmolar microenvironment, glycolysis mediating metabolic reprogramming, and pyroptosis were explored clinically, in vitro, and in vivo. Data from DED clinical samples indicated that the expression of glycolysis and pyroptosis-related genes, including PKM2 and GSDMD, was significantly upregulated and that the secretion of IL-1β significantly increased. In vitro, the indirect coculture of macrophages derived from THP-1 and human corneal epithelial cells (HCECs) was used to discuss the interaction among cells. The hyperosmolar environment was found to greatly induce HCECs’ metabolic reprogramming, which may be the primary cause of the subsequent inflammation in macrophages upon the activation of the related gene and protein expression. 2-Deoxy-d-glucose (2-DG) could inhibit the glycolysis of HCECs and subsequently suppress the pyroptosis of macrophages. In vivo, 2-DG showed potential efficacy in relieving DED activity and could significantly reduce the overexpression of genes and proteins related to glycolysis and pyroptosis. In summary, our findings suggested that hyperosmolar-induced glycolytic reprogramming played an active role in promoting DED inflammation by mediating pyroptosis.

Keywords： dry eye disease     glycolytic reprogramming     pyroptosis     inflammation     2-DG    

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Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 33-39 doi: 10.1007/s11684-011-0114-1

Abstract: The precise mechanisms underlying migration of MSCs into the injured tissue are still not fully understoodreview will briefly summarize the regulatory facors and signaling transduction pathways involved in migrationA better understanding of the molecular mechanisms involved in the migration of MSCs will help us to

Keywords： mesenchymal stem cells     migration     molecular mechanisms     signaling pathway    

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Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 4,   Pages 346-350 doi: 10.1007/s11705-009-0256-8

Abstract: The purpose of this study was to investigate whether moisture migration and sugar crystallization playThe migration of water was monitored with changes of water activity in different physical domains of

Keywords： inner-layer     agglomerated     IMF     moisture migration     crystallization    

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Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 312-321 doi: 10.1007/s11684-015-0401-3

Abstract: cells, as well as the tumorigenicity, whereas DAB2 overexpression enhanced LNCaP cell migrationFurther investigation showed that DAB2 regulated the cell migration associated genes

Keywords： DAB2     prostate cancer     migration     invasion     acetylation    

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Influence of initial curing conditions and exposure environments on chloride migration in concrete using

Wen XUE, Weiliang JIN, Hiroshi YOKOTA,

Frontiers of Structural and Civil Engineering 2010, Volume 4, Issue 3,   Pages 348-353 doi: 10.1007/s11709-010-0077-3

Abstract: investigate the influence of initial curing conditions and exposure environments on chloride ions’ migrationchloride ions passing through the specimen’s section was monitored in the accelerated chloride migration

Keywords： durability     effective diffusion coefficient     steady-state     migration test    

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Fighting for the poverty: a case study for human migration in the context of sustainable dryland farming

Yongqing MA, Jie CHEN, Shuqi DONG, Lun SHAN

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 1,   Pages 62-68 doi: 10.15302/J-FASE-2014027

Abstract: improvements to the Southern Ningxia Hilly Area and considers future development in the context of migration

Keywords： agricultural production     animal husbandry     development strategy     ecological migration    

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Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Frontiers of Medicine 2014, Volume 8, Issue 4,   Pages 456-463 doi: 10.1007/s11684-014-0353-z

Abstract: investigate the effects of miRNA-200c (miR-200c) on the biological behavior and mechanism of proliferation, migrationThe proliferation, migration, and invasion abilities of Du145 cells were detected by CCK8 assays, migrationDu145 cells were then transfected with miR-200c mimics and displayed lower abilities of proliferation, migrationinhibit the proliferation of the prostate cancer cell line Du145; likewise, miR-200c could inhibit migration

Keywords： miR-200c     proliferation     migration     invasion     prostate cancer     Du145 cell     ZEB1    

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A microarray study of altered gene expression during melanoblasts migration in normal pigmented White

Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG

Frontiers of Agricultural Science and Engineering 2014, Volume 1, Issue 4,   Pages 299-306 doi: 10.15302/J-FASE-2014040

Abstract: ventral regions of the embryos owing to differences in gene expression in the process of melanoblasts migrationThe genes with significantly altered expression involved in melanoblast migration and development suggestedthat different microenvironments resulted in the abnormal melanoblast migration in Silky Fowl, although

Keywords： Silky Fowl     White Leghorn     melanoblast migration     gene expression    

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Migration and fate of polycyclic aromatic hydrocarbons in bioretention systems with different media:

Frontiers of Environmental Science & Engineering 2023, Volume 18, Issue 4, doi: 10.1007/s11783-024-1802-9

Abstract:

● Bioretention systems showed > 92% load reduction rates of PAHs.

Keywords： Bioretention     Polycyclic aromatic hydrocarbons     HYDRUS-1D     Model simulation     Migration    

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Influence of the intensity and loading time of direct current electric field on the directional migration

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 286-296 doi: 10.1007/s11684-016-0456-9

Abstract: Exogenic electric fields can effectively accelerate bone healing and remodeling through the enhanced migrationThis study aimed to determine the following: (1) the direction of rat BMSC (rBMSC) migration upon exposureMoreover, when CXCR4 was inhibited, rBMSC migration due to DCEF was partially blocked.These findings indicated that DCEF can effectively induce rBMSC migration.The SDF-1/CXCR4 signaling pathway may play an important role in regulating the DCEF-induced migration

Keywords： DCEF     migration     osteogenesis differentiation     rBMSCs     SDF-1/CXCR-4    

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Occurrence and migration of microplastics and plasticizers in different wastewater and sludge treatment

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 11, doi: 10.1007/s11783-022-1577-9

Abstract:

● Reduce the quantifying MPs time by using Nile red staining.

Keywords： Microplastics     Municipal wastewater treatment plant     Phthalate esters     Thermal hydrolysis    

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Biomimetic Macrophage–Fe3O4@PLGA Particle-Triggered Intelligent Catalysis for Killing Multidrug-Resistant

Jieni Fu,Xiangmei Liu,Zhaoyang Li,Yufeng Zheng,Yu Zhang,Hui Jiang,Yanqin Liang,Shengli Zhu,Zhenduo Cui,Shuilin Wu,

Engineering doi: 10.1016/j.eng.2023.05.022

Abstract: selective biocatalytic property of macrophages, consisting of an intelligent controlling center (a living macrophage

Keywords： Multidrug-resistant Escherichia coli     Macrophage–Fe3O4@PLGA particles     Biomimetic intelligent catalysis    

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Applications of atomic force microscopy in immunology

Jiping Li, Yuying Liu, Yidong Yuan, Bo Huang

Frontiers of Medicine 2021, Volume 15, Issue 1,   Pages 43-52 doi: 10.1007/s11684-020-0769-6

Abstract: Cellular mechanics also acts as a fundamental mediator in complicated immune responses, such as cell migration

Keywords： cellular mechanics     atomic force microscopy     neutrophil extracellular trap     macrophage phagocytosis     pore    

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Title Author Date Type Operation

by Transcriptomics and Multiscale Bioassays of Active Components in Xuanfeibaidu Formula to Suppress Macrophage-Mediated

Lu Zhao, Hao Liu, Yingchao Wang, Shufang Wang, Dejin Xun, Yi Wang, Yiyu Cheng, Boli Zhang

Journal Article

Theoretical study on the mechanism of sulfur migration to gas in the pyrolysis of benzothiophene

Journal Article

Hyperosmolarity promotes macrophage pyroptosis by driving the glycolytic reprogramming of corneal epithelial

Journal Article

Regulatory factors of mesenchymal stem cell migration into injured tissues and their signal transduction

Li LI, Jianxin JIANG

Journal Article

Effects of sucrose crystallization and moisture migration on the structural changes of a coated intermediate

Tiancheng LI, Peng ZHOU, Theodore P. LABUZA

Journal Article

Disabled homolog 2 is required for migration and invasion of prostate cancer cells

Yinyin Xie,Yuanliang Zhang,Lu Jiang,Mengmeng Zhang,Zhiwei Chen,Dan Liu,Qiuhua Huang

Journal Article

Influence of initial curing conditions and exposure environments on chloride migration in concrete using

Wen XUE, Weiliang JIN, Hiroshi YOKOTA,

Journal Article

Fighting for the poverty: a case study for human migration in the context of sustainable dryland farming

Yongqing MA, Jie CHEN, Shuqi DONG, Lun SHAN

Journal Article

Effects of miR-200c on the migration and invasion abilities of human prostate cancer Du145 cells and

Runlin Shi,Haibing Xiao,Tao Yang,Lei Chang,Yuanfeng Tian,Bolin Wu,Hua Xu

Journal Article

A microarray study of altered gene expression during melanoblasts migration in normal pigmented White

Yulin LI,Deping HAN,Junying LI,Dawn KOLTES,Xuemei DENG

Journal Article

Migration and fate of polycyclic aromatic hydrocarbons in bioretention systems with different media:

Journal Article

Influence of the intensity and loading time of direct current electric field on the directional migration

Xiaoyu Wang,Yuxuan Gao,Haigang Shi,Na Liu,Wei Zhang,Hongbo Li

Journal Article

Occurrence and migration of microplastics and plasticizers in different wastewater and sludge treatment

Journal Article

Biomimetic Macrophage–Fe3O4@PLGA Particle-Triggered Intelligent Catalysis for Killing Multidrug-Resistant

Jieni Fu,Xiangmei Liu,Zhaoyang Li,Yufeng Zheng,Yu Zhang,Hui Jiang,Yanqin Liang,Shengli Zhu,Zhenduo Cui,Shuilin Wu,

Journal Article

Applications of atomic force microscopy in immunology

Jiping Li, Yuying Liu, Yidong Yuan, Bo Huang

Journal Article